The Dance between our Microbiome and our DNA

Personalised healthcare is based on the premise that we are all unique – through deeper understanding of an individuals’ genotype, together with other functional biomarkers we can transform the healthcare environment to achieve:

  • Prediction and prevention of disease
  •   More precise diagnoses
  •   Personalised and targeted interventions andµµ
       A more participatory role for patients.1

This workshop will highlight the importance of this emerging field through use of practical, gut-health examples in clinical care, and how, through adopting this approach we can take a step closer to realising the above.
We will explore the interaction between HLA genes, risk for gluten intolerance and sensitivity, and  functional gut biomarkers, antigliadin antibodies and zonulin2–4. Evidence around these associations and impact on health will be highlighted, and practical guidelines to improve outcomes will be presented. Other gene-phenotype-environment interactions that will be presented include, the role of histamine genes and their effect on gut health5, as well as the crosstalk between gut health and detoxification pathways6.